MicroRNA Market Outlook 2031:
MicroRNA market Size was estimated to be worth $0.32 billion USD. The AMR Group projects that the market will increase at a compound annual growth rate (CAGR) of 19.5% from 2022 to 2031, reaching US$1.8 billion.
MicroRNAs (miRNAs) are naturally occurring small RNAs that regulate gene expression post-transcriptionally. MiRNA research in allergies is expanding because miRNAs are important regulators of gene expression and great possibilities for biomarkers. Preclinical studies are now being conducted on miRNA mimics and inhibitors as novel medicinal drugs.
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What are MicroRNAs?
MicroRNAs are small, non-coding RNA molecules, typically about 18-25 nucleotides in length, that regulate gene expression by binding to messenger RNAs (mRNAs) and inhibiting their translation or causing their degradation. Their role in regulating genes involved in cell cycle, apoptosis, and differentiation has made them of particular interest in oncology, cardiology, neurology, and immunology.
Market Dynamics:
Operators
Growing application of microRNA
The industry is also being driven by the growing usage of microRNA as a biomarker. Because these biomarkers are highly reproducible and robust in comparison to conventional processes, they hold great significance in genome-wide population research and data-driven methodologies. These compounds therefore present a possible therapeutic option for the creation of biomarkers. Moreover, liquid-based biopsies are becoming more and more important in the development and finding of biomarkers.
Increased investigation of the possibilities of miRNA biomarkers
In the near future, it is anticipated that a spike in research into the applications of miRNA biomarkers in prognosis, diagnosis, and treatments will favour market expansion. For example, in January 2020, researchers explored the potential of miRNA detected in peripheral blood as a biomarker for the diagnosis of Bipolar II disorder (BD-II) using next-generation sequencing. MiRNAs may offer a non-invasive way to identify further neurodegenerative illnesses.
Key Trends in the MicroRNA Market
Integration with Artificial Intelligence (AI) AI and machine learning are playing an increasingly important role in miRNA research, enabling faster analysis and identification of patterns in miRNA expression. AI-powered tools are being used to predict miRNA targets and functions, thus speeding up the drug discovery process and offering new insights into disease mechanisms.
Non-Invasive Diagnostic Technologies Liquid biopsies are becoming a popular alternative to traditional tissue biopsies, thanks to miRNAs’ stability in bodily fluids like blood, saliva, and urine. This non-invasive approach is being explored for diagnosing a variety of conditions, including cancer and cardiovascular diseases, and could soon become a standard diagnostic tool.
Collaborations Between Academic Institutions and Industry Academic institutions and biotech firms are collaborating to translate basic miRNA research into clinical applications. These partnerships aim to harness academic expertise while leveraging industry resources for large-scale production, regulatory approvals, and commercialization.
Expansion into New Therapeutic Areas While oncology has been the primary focus of miRNA research, there is growing interest in using miRNA-based therapeutics for cardiovascular, neurodegenerative, and metabolic diseases. The versatility of miRNAs in modulating multiple biological pathways makes them attractive for targeting complex diseases.
Market Opportunities:
advances in technology
The development of new technologies to enhance the sensitivity and selectivity of miRNA detection fuels the expansion of the microRNA market. Among the recently created techniques for miRNA detection are enzyme-free amplification, RCA-based, DSN-based, LAMP-based, and nanoparticle-based amplification. In a similar vein, in January 2020, scientists created a program-based isothermal amplification method for precise and accurate digital detection of miRNA. Because the technology relies on signal amplification rather than PCR-based methods, which replicate the desired sequence directly, contamination can be minimized.
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Challenges Facing the MicroRNA Market
Despite its potential, the microRNA market faces several challenges. One major hurdle is the difficulty in delivering miRNA-based therapies to target tissues without degradation or off-target effects. Additionally, regulatory pathways for miRNA therapeutics are still evolving, and obtaining FDA or EMA approval can be a lengthy and uncertain process. Intellectual property issues also pose challenges, as many patents related to miRNA technologies overlap, creating legal complexities.
Market Segments:
By Product and Services
- Research Tools
- Services
By Technology
- Real Time Polymerase Chain Reaction
- Microarray
- Next Generation Sequencing (NGS)
- Immunoassay
By Application
- Cancer
- Immunological Disorder
- Infectious Diseases
- Cardiovascular Disease
- Neurological Disease
By End User
- Academic and Research Institutes
- Biopharmaceutical Companies
- Contract Research Organizations
- Diagnostic Centres
Market Regional Analysis:
In terms of geography, North America held the biggest revenue share of 45.8% in 2020 and led the microRNA market. Numerous causes, including the region's considerable RD activity, the presence of important firms, and the well-established infrastructure for proteomics, genomics, and oncology research, are responsible for its expansion. Nonetheless, local businesses are getting their miRNA biomarkers' patents approved. For example, Dimer was granted a U.S. Patent in May 2020 for their miRNA-based techniques for the identification and monitoring of brain aging.
The microRNA market is anticipated to expand at the fastest rate in Asia Pacific, with a projected growth rate of 20.6% between 2021 and 2028. The market's expansion in the area is mainly due to the quick development of genomic research and the adoption of new instruments to aid in research projects. Using microarray-based miRNA profiling, Chinese researchers discovered in February 2021 that blood microRNA may serve as a possible diagnostic for pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome (HSOS).
Future Outlook of the MicroRNA Market
The microRNA market is poised for substantial growth over the next decade. According to industry reports, the global microRNA market size was valued at around $250 million in 2021 and is projected to grow at a compound annual growth rate (CAGR) of over 17% through 2028. This growth is expected to be fueled by ongoing research into miRNA’s therapeutic potential, expanding applications in diagnostics, and the increasing role of personalized medicine.
Leading Key Companies Involved in this report are:
- Agilent Technologies Inc
- Biodynamics Laboratory Inc.
- Bio Genex
- Bio-Rad Laboratories, Inc.
- Gene Capoeira, Inc.
- General Electric Company
- Horizon Discovery Ltd.
- Illumina, Inc.
- Merck KGaA
- Miltonic Biotech
- Nano String
- New England Bio labs
- Norgon Biotech Corp.
- Fisher Scientific, Inc.
- among others.
Conclusion
MicroRNAs represent a frontier in modern medicine, offering opportunities for novel diagnostics and therapeutics. While challenges remain, the market’s rapid growth indicates strong interest from both academia and industry. As research continues to unlock the full potential of miRNAs in disease treatment and prevention, their impact on healthcare could be transformative. Companies that can navigate regulatory hurdles and overcome technical challenges stand to reap significant benefits as this market continues to evolve.
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